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Ambulatory clients should be advised to stop partaking in these types of activities right until it is understood that they don't turn out to be drowsy or dizzy from promethazine and phenylephrine therapy. Kids should be supervised to prevent probable harm in bicycle Using or in other dangerous actions.
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Ventricular untimely beats and short paroxysms of ventricular tachycardia may come about. Headache may be a symptom of hypertension. Bradycardia could also be found early in phenylephrine overdosage by way of stimulation of baroreceptors.
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Epinephrine: Because of the possible for promethazine to reverse epinephrine’s vasopressor outcome, epinephrine shouldn't be employed to deal with hypotension connected to promethazine overdose.
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Phenylephrine need to be made use of with warning in clients with heart problems, specially hypertension.
A residence teaspoon will not be an precise measuring product and may lead to overdosage [see Warnings and Precautions (five.7)]. For prescriptions wherever a measuring device just isn't furnished, a pharmacist can provide an appropriate measuring gadget and can provide Guidance for measuring the proper dose. Do not overfill. Rinse the measuring unit with h2o after Every use.
Promethazine hydrochloride and phenylephrine hydrochloride syrup should be made use of with caution in pediatric sufferers 2 years of age and older (see WARNINGS-Use in Pediatric Sufferers)